•Updated
to reflect the shift to STR technology
•Addresses the benefits and limitations of mitochondrial DNA
typing and Y-STRs
•Reflects the shift to automation and computerization
•Covers legal admissibility of STR technology and older methods
•Discusses various statistical approaches
•Includes unusual case studies for added interest
•Combines technological, forensic, and legal considerations for
a comprehensive approach
•Presents over 100 figures, 18 in full color
Significant advances in DNA analysis techniques have surfaced
since the 1997 publication of the bestselling An Introduction
to Forensic DNA Analysis. DNA typing has become increasingly
automated and miniaturized. Also, with the advent of Short
Tandem Repeat (STR) technology, even the most minute sample
of degraded DNA can yield a profile, providing valuable case
information. However, just as the judicial system slowly
and reluctantly accepted RFLP and AmpliType® PM+DQA1
typing, it is now scrutinizing the admissibility of STRs.
Acknowledging STR typing as the current system of choice,
An Introduction to Forensic DNA Analysis, Second Edition
translates new and established concepts into plain English
so that laypeople can gain insight into how DNA analysis
works, from sample collection to interpretation of results.
In response to the shift toward more efficient techniques,
the authors cover the legal admissibility of STR typing,
expand the chapter on DNA databases, and revise the section
on automated analysis. They also present key decisions and
appellate or supreme court rulings that provide precedent
at the state and federal levels.
Discussing forensic DNA issues from both a scientific and
a legal perspective, the authors of An Introduction to Forensic
DNA Analysis, Second Edition present the material in a manner
understandable by professionals in the legal system, law
enforcement, and forensic science. They cover general principles
in a clear fashion and include a glossary of terms and other
useful appendices for easy reference.
Table of Contents:
Introduction
The Nature of Physical Evidence
Science and the Law
Principles and Processes of Criminalistics
Fingerprints and DNA
Conventional Blood Typing
The Collection and Preservation of Physical Evidence
Extraneous Substances
Collection of Evidence
Preservation of Evidence
Evaluation of Evidence
A Short History of DNA Typing
The Scientific Basis of DNA Typing
Why DNA?
An Introduction to Human Genetics
An Introduction to the Molecular Biology of DNA
Two Kinds of Variation
Enzymes, the Workhorses of the Biological World
An Overview of Forensic DNA Typing Systems
RFLP Analysis
PCR Amplification
What Kinds of Samples Can be Analyzed?
How Much Sample Do You Need?
Procedures for Forensic DNA Analysis
Isolation of DNA
Determining Quality and Quantity of DNA
RFLP Analysis
|
PCR Amplification
Analysis of PCR Product
Automated Analysis Systems
Interpretation of DNA Typing Results
Complicating Factors
System Specific Interpretational Issues
Summary of DNA Interpretation Issues
Assessing the Strength of the Evidence
Determination of Genetic Concordance
Evaluation of Results
Frequency Estimate Calculations
Population Substructure
Likelihood Ratios
When is a DNA Profile Unique?
The DNA Databank
Premise of a Databank
The Difference between a Databank and a Database
Elements of a Successful Databank
Summary
Quality Assurance
Certification and Accreditation
SWDAM (formerly TWGDAM)
NRC I and II
Federal DNA Advisory Board
Admissibility Standards - Science on Trial in the
Courtroom
Frye, Daubert, and the Federal Rules of Evidence
DNA - Some Landmark Cases
The State of the Debate
Epilogue
Glossary
Appendices |
ISBN 0849302331 Hardcover
312 pages
6.25"x9.5"
retail $88.99
Our Price $70.95
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